Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.

Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.

Low-penetrance genetic variants have been increasingly recognized to influence the risk of tumor development. Risk variants for colorectal cancer (CRC) have been mapped to chromosome positions 8q23.3, 8q24, 9p24.1, 10p14, 11q23, 14q22.2, 15q13, 16q22.1, 18q21, 19q13.1 and 20p12.3. In particular, the...

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Bibliographic Details
Main Authors: Janelle M Hoskins, Pei-Shi Ong, Temitope O Keku, Joseph A Galanko, Christopher F Martin, Clint A Coleman, Michelle Wolfe, Robert S Sandler, Howard L McLeod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407042?pdf=render

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http://europepmc.org/articles/PMC3407042?pdf=render

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