Effects of calorie restriction and diet-induced obesity on murine colon carcinogenesis, growth and inflammatory factors, and microRNA expression.

Obesity is an established colon cancer risk factor, while preventing or reversing obesity via a calorie restriction (CR) diet regimen decreases colon cancer risk. Unfortunately, the biological mechanisms underlying these associations are poorly understood, hampering development of mechanism-based ap...

Full description

Bibliographic Details
Main Authors: Susan E Olivo-Marston, Stephen D Hursting, Susan N Perkins, Aaron Schetter, Mohammed Khan, Carlo Croce, Curtis C Harris, Jackie Lavigne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3986228?pdf=render