Enteric Neural Cells From Hirschsprung Disease Patients Form Ganglia in Autologous Aneuronal ColonSummary

Background & Aims: Hirschsprung disease (HSCR) is caused by failure of cells derived from the neural crest (NC) to colonize the distal bowel in early embryogenesis, resulting in absence of the enteric nervous system (ENS) and failure of intestinal transit postnatally. Treatment is by distal bowe...

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Bibliographic Details
Main Authors: Benjamin N. Rollo, Dongcheng Zhang, Lincon A. Stamp, Trevelyan R. Menheniott, Lefteris Stathopoulos, Mark Denham, Mirella Dottori, Sebastian K. King, John M. Hutson, Donald F. Newgreen
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X15001605