Generation of a human iPSC line (MPIi006-A) from a patient with Pelizaeus-Merzbacher disease

Generation of a human iPSC line (MPIi006-A) from a patient with Pelizaeus-Merzbacher disease

We established a human induced pluripotent stem cells (hiPSC) line (MPIi006-A) from fibroblasts of a 20-year-old male Pelizaeus-Merzbacher disease (PMD) patient with a hemizygous 643C>T mutation in proteolipid protein 1 (PLP1) gene using a retroviral delivery of OCT4, SOX2, KLF4 and c-MYC. The MP...

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Bibliographic Details
Main Authors: Kee-Pyo Kim, Juyong Yoon, Borami Shin, Albrecht Röpke, Dong Wook Han, Hans R. Schöler
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120301409

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http://www.sciencedirect.com/science/article/pii/S1873506120301409

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