Novel gene-by-environment interactions: APOB and NPC1L1 variants affect the relationship between dietary and total plasma cholesterol[S]

Novel gene-by-environment interactions: APOB and NPC1L1 variants affect the relationship between dietary and total plasma cholesterol[S]

Cardiovascular disease (CVD) is the leading cause of death in developed countries. Plasma cholesterol level is a key risk factor in CVD pathogenesis. Genetic and dietary variation both influence plasma cholesterol; however, little is known about dietary interactions with genetic variants influencing...

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Bibliographic Details
Main Authors: Daniel S. Kim, Amber A. Burt, Jane E. Ranchalis, Ella R. Jarvik, Elisabeth A. Rosenthal, Thomas S. Hatsukami, Clement E. Furlong, Gail P. Jarvik
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Journal of Lipid Research
Subjects:
dietary cholesterol
total cholesterol
cardiovascular disease
Niemann-Pick C1-like 1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520421881

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520421881

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