miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells

miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells

Abstract Background Head and neck squamous cell carcinoma (HNSCC) is the sixth leading cancer worldwide. They are typically characterized by a high incidence of local recurrence, which is the most common cause of death in HNSCC patients. TP53 is the most frequently mutated gene in HNSCC and patients...

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Bibliographic Details
Main Authors: Mahrou Vahabi, Claudio Pulito, Andrea Sacconi, Sara Donzelli, Marco D’Andrea, Valentina Manciocco, Raul Pellini, Paola Paci, Giuseppe Sanguineti, Lidia Strigari, Giuseppe Spriano, Paola Muti, Pier Paolo Pandolfi, Sabrina Strano, Shahrokh Safarian, Federica Ganci, Giovanni Blandino
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
miRNAs
TP53 mutations
miR-96-5p
Head and neck cancer
Local recurrence
Migration
Online Access:http://link.springer.com/article/10.1186/s13046-019-1119-x

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http://link.springer.com/article/10.1186/s13046-019-1119-x

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