Hyaluronan-CD44 interaction promotes growth of decidual stromal cells in human first-trimester pregnancy.

Hyaluronan (HA) and its receptor CD44 are expressed at the maternal-fetal interface, but its role in early pregnancy remains unclear. Here, we found that primary decidual stromal cells (DSCs) continuously secreted HA and expressed its receptor CD44. Pregnancy-associated hormones up-regulated HA synt...

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Bibliographic Details
Main Authors: Rui Zhu, Song-Cun Wang, Chan Sun, Yu Tao, Hai-Lan Piao, Xiao-Qiu Wang, Mei-Rong Du, Da-Jin Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3777984?pdf=render