Glutamine Addiction and Therapeutic Strategies in Lung Cancer

Glutamine Addiction and Therapeutic Strategies in Lung Cancer

Lung cancer cells are well-documented to rewire their metabolism and energy production networks to support rapid survival and proliferation. This metabolic reorganization has been recognized as a hallmark of cancer. The increased uptake of glucose and the increased activity of the glycolytic pathway...

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Bibliographic Details
Main Authors: Karolien Vanhove, Elien Derveaux, Geert-Jan Graulus, Liesbet Mesotten, Michiel Thomeer, Jean-Paul Noben, Wanda Guedens, Peter Adriaensens
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
Lung cancer
metabolism
glutamine
glutaminolysis
pathways
targeted treatment
Online Access:http://www.mdpi.com/1422-0067/20/2/252

Internet

http://www.mdpi.com/1422-0067/20/2/252

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