Attenuation of multiple Nef functions in HIV-1 elite controllers

Attenuation of multiple Nef functions in HIV-1 elite controllers

<p>Abstract</p> <p>Background</p> <p>Impaired HIV-1 Gag, Pol, and Env function has been described in elite controllers (EC) who spontaneously suppress plasma viremia to < 50 RNA copies/mL; however, activity of the accessory protein Nef remains incompletely characteri...

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Bibliographic Details
Main Authors: Mwimanzi Philip, Markle Tristan J, Martin Eric, Ogata Yoko, Kuang Xiaomei T, Tokunaga Michiyo, Mahiti Macdonald, Pereyra Florencia, Miura Toshiyuki, Walker Bruce D, Brumme Zabrina L, Brockman Mark A, Ueno Takamasa
Format: Article
Language:English
Published: BMC 2013-01-01
Series:Retrovirology
Subjects:
HIV-1
Nef
Elite controllers
Human Leukocyte Antigen (HLA) class I
Immune escape
Replication capacity
HLA-B*57
Online Access:http://www.retrovirology.com/content/10/1/1

Internet

http://www.retrovirology.com/content/10/1/1

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