Characterization of structural features controlling the receptiveness of empty class II MHC molecules.

Characterization of structural features controlling the receptiveness of empty class II MHC molecules.

MHC class II molecules (MHC II) play a pivotal role in the cell-surface presentation of antigens for surveillance by T cells. Antigen loading takes place inside the cell in endosomal compartments and loss of the peptide ligand rapidly leads to the formation of a non-receptive state of the MHC molecu...

Full description

Bibliographic Details
Main Authors: Bernd Rupp, Sebastian Günther, Talat Makhmoor, Andreas Schlundt, Katharina Dickhaut, Shashank Gupta, Iqbal Choudhary, Karl-Heinz Wiesmüller, Günther Jung, Christian Freund, Kirsten Falk, Olaf Rötzschke, Ronald Kühne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3077389?pdf=render

Internet

http://europepmc.org/articles/PMC3077389?pdf=render

Similar Items