Characterization of structural features controlling the receptiveness of empty class II MHC molecules.
MHC class II molecules (MHC II) play a pivotal role in the cell-surface presentation of antigens for surveillance by T cells. Antigen loading takes place inside the cell in endosomal compartments and loss of the peptide ligand rapidly leads to the formation of a non-receptive state of the MHC molecu...
Main Authors: | Bernd Rupp, Sebastian Günther, Talat Makhmoor, Andreas Schlundt, Katharina Dickhaut, Shashank Gupta, Iqbal Choudhary, Karl-Heinz Wiesmüller, Günther Jung, Christian Freund, Kirsten Falk, Olaf Rötzschke, Ronald Kühne |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3077389?pdf=render |
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