AGER -429T/C is associated with an increased lung disease severity in cystic fibrosis.

AGER -429T/C is associated with an increased lung disease severity in cystic fibrosis.

The clinical course of cystic fibrosis (CF) varies between patients bearing identical CFTR mutations, suggesting the involvement of modifier genes. We assessed the association of lung disease severity with the variant AGER -429 T/C, coding for RAGE, a pro-inflammatory protein, in CF patients from th...

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Bibliographic Details
Main Authors: Julie Beucher, Pierre-Yves Boëlle, Pierre-François Busson, Céline Muselet-Charlier, Annick Clement, Harriet Corvol, French C F Modifier Gene Study Investigators
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3408394?pdf=render

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http://europepmc.org/articles/PMC3408394?pdf=render

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