Somatic LKB1 mutations promote cervical cancer progression.

Human Papilloma Virus (HPV) is the etiologic agent for cervical cancer. Yet, infection with HPV is not sufficient to cause cervical cancer, because most infected women develop transient epithelial dysplasias that spontaneously regress. Progression to invasive cancer has been attributed to diverse ho...

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Bibliographic Details
Main Authors: Shana N Wingo, Teresa D Gallardo, Esra A Akbay, Mei-Chi Liang, Cristina M Contreras, Todd Boren, Takeshi Shimamura, David S Miller, Norman E Sharpless, Nabeel Bardeesy, David J Kwiatkowski, John O Schorge, Kwok-Kin Wong, Diego H Castrillon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2660434?pdf=render