Molecular Insights into the Oxygen-Sensing Pathway and Erythropoietin Expression Regulation in Erythropoiesis

Molecular Insights into the Oxygen-Sensing Pathway and Erythropoietin Expression Regulation in Erythropoiesis

Erythropoiesis is regulated by several factors, including the oxygen-sensing pathway as the main regulator of erythropoietin (EPO) synthesis in the kidney. The release of EPO from the kidney and its binding to the EPO receptor (EPOR) on erythrocyte progenitor cells in the bone marrow results in incr...

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Bibliographic Details
Main Authors: Jana Tomc, Nataša Debeljak
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
erythropoiesis
oxygen-sensing pathway
hypoxia-inducible factor
erythropoietin
molecular mechanisms
post-translational modifications
Online Access:https://www.mdpi.com/1422-0067/22/13/7074

Internet

https://www.mdpi.com/1422-0067/22/13/7074

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