Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer.

Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer.

BACKGROUND: Regulatory T cells (Treg) expressing the transcription factor forkhead-box protein P3 (Foxp3) have been identified to counteract anti-tumor immune responses during tumor progression. Besides, Foxp3 presentation by cancer cells itself may also allow them to evade from effector T-cell resp...

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Bibliographic Details
Main Authors: Mia Kim, Tanja Grimmig, Martin Grimm, Maria Lazariotou, Eva Meier, Andreas Rosenwald, Igor Tsaur, Roman Blaheta, Uwe Heemann, Christoph-Thomas Germer, Ana Maria Waaga-Gasser, Martin Gasser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3559740?pdf=render

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http://europepmc.org/articles/PMC3559740?pdf=render

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