Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer.
BACKGROUND: Regulatory T cells (Treg) expressing the transcription factor forkhead-box protein P3 (Foxp3) have been identified to counteract anti-tumor immune responses during tumor progression. Besides, Foxp3 presentation by cancer cells itself may also allow them to evade from effector T-cell resp...
Main Authors: | Mia Kim, Tanja Grimmig, Martin Grimm, Maria Lazariotou, Eva Meier, Andreas Rosenwald, Igor Tsaur, Roman Blaheta, Uwe Heemann, Christoph-Thomas Germer, Ana Maria Waaga-Gasser, Martin Gasser |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3559740?pdf=render |
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