MICAL-L2 Is Essential for c-Myc Deubiquitination and Stability in Non-small Cell Lung Cancer Cells

MICAL-L2 Is Essential for c-Myc Deubiquitination and Stability in Non-small Cell Lung Cancer Cells

Objectives: MICAL-L2, a member of the molecules interacting with the CasL (MICAL) family, was reported to be highly expressed in several types of cancers, however, the roles of MICAL-L2 in NSCLC pathogenesis remain to be explored. This study is designed to clarify the mechanisms by which MICAL-L2 pa...

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Bibliographic Details
Main Authors: Pengxiang Min, Lin Zhang, Yueyuan Wang, Chenxiang Qi, Yixuan Song, Maria Bibi, Yujie Zhang, Yadong Ma, Xuyang Zhao, Minjie Yu, Jun Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
c-Myc
MICAL-L2
NSCLC
proliferation
deubiquitination
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.575903/full

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https://www.frontiersin.org/articles/10.3389/fcell.2020.575903/full

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