A Novel Recombinant Virus-Like Particles Displaying B and T Cell Epitopes of Japanese Encephalitis Virus Offers Protective Immunity in Mice and Guinea Pigs

A Novel Recombinant Virus-Like Particles Displaying B and T Cell Epitopes of Japanese Encephalitis Virus Offers Protective Immunity in Mice and Guinea Pigs

Virus-like particles (VLPs) are non-replicative vectors for the delivery of heterologous epitopes and are considered one of the most potent inducers of cellular and humoral immune responses in mice and guinea pigs. In the present study, VLP-JEVe was constructed by the insertion of six Japanese encep...

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Bibliographic Details
Main Authors: Muhammad Naveed Anwar, Chunying Jiang, Di Di, Junjie Zhang, Shuang Guo, Xin Wang, Muddassar Hameed, Abdul Wahaab, Donghua Shao, Zongjie Li, Ke Liu, Beibei Li, Yafeng Qiu, Zhiyong Ma, Jianchao Wei
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Vaccines
Subjects:
Japanese encephalitis virus
porcine parvovirus
virus-like particle
immunogenicity
Online Access:https://www.mdpi.com/2076-393X/9/9/980

Internet

https://www.mdpi.com/2076-393X/9/9/980

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