Using digital RNA counting and flow cytometry to compare mRNA with protein expression in acute leukemias.

BACKGROUND: The diagnosis of malignant hematologic diseases has become increasingly complex during the last decade. It is based on the interpretation of results from different laboratory analyses, which range from microscopy to gene expression profiling. Recently, a method for the analysis of RNA ph...

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Bibliographic Details
Main Authors: Paula Fernandez, Max Solenthaler, Olivier Spertini, Stephane Quarroz, Alicia Rovo, Pierre-Yves Lovey, Leda Leoncini, Sylvie Ruault-Jungblut, Mathilde D'Asaro, Olivier Schaad, Mylène Docquier, Patrick Descombes, Thomas Matthes, Swiss Cytometry Society
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3494663?pdf=render