The transcriptome-wide association search for genes and genetic variants which associate with BMI and gestational weight gain in women with type 1 diabetes

The transcriptome-wide association search for genes and genetic variants which associate with BMI and gestational weight gain in women with type 1 diabetes

Abstract Background Clinical data suggest that BMI and gestational weight gain (GWG) are strongly interconnected phenotypes; however, the genetic basis of the latter is rather unclear. Here we aim to find genes and genetic variants which influence BMI and/or GWG. Methods We have genotyped 316 type 1...

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Bibliographic Details
Main Authors: Agnieszka H. Ludwig-Słomczyńska, Michał T. Seweryn, Przemysław Kapusta, Ewelina Pitera, Urszula Mantaj, Katarzyna Cyganek, Paweł Gutaj, Łucja Dobrucka, Ewa Wender-Ożegowska, Maciej T. Małecki, Paweł P. Wołkow
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Molecular Medicine
Subjects:
Obesity
BMI
Gestational weight gain (GWG)
Transcriptomic-wide association study (TWAS)
Association analysis
Online Access:https://doi.org/10.1186/s10020-020-00266-z

Internet

https://doi.org/10.1186/s10020-020-00266-z

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