FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia

<p>Abstract</p> <p>Background</p> <p>Interaction with the surrounding mesenchyme is necessary for development of endodermal organs, and Fibroblast growth factors have recently emerged as mesenchymal-expressed morphogens that direct endodermal morphogenesis. The fibrobla...

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Bibliographic Details
Main Authors: Kobberup Sune, Norgaard Gitte A, Nyeng Pia, Jensen Jan
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/8/2