Specific zinc finger‐induced methylation of PD‐L1 promoter inhibits its expression

DNA methylation of promoter regions is often associated with epigenetic silencing of gene expression, and DNA methyltransferase (DNMTs) has been used to suppress gene expression. In order to explore the synergistic roles of two methyltransferase members Dnmt3a and Dnmt1, we constructed expression pl...

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Bibliographic Details
Main Authors: Xue Li, Zhenni Wang, Jiansheng Huang, Huazao Luo, Sibo Zhu, Han Yi, Liuhai Zheng, Bo Hu, Lili Yu, Lingzhi Li, Jun Xie, Naishuo Zhu
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12568