Construction of an Adenovirus Vaccine Expressing the Cross-reactive Antigen AMA1 for Neospora caninum and Toxoplasma gondii and Its Immune Response in an Animal Model

Construction of an Adenovirus Vaccine Expressing the Cross-reactive Antigen AMA1 for Neospora caninum and Toxoplasma gondii and Its Immune Response in an Animal Model

Background: We aimed to construct an adenovirus expressing a cross-reactive fragment of the apical membrane antigen 1 (AMA1) antigen and evaluated the concomitant immune response in BABL/c mice, allowing protection against N. caninum and T. gondii infection. Methods: The study was conducted in Agr...

Full description

Bibliographic Details
Main Authors: Lijun JIA, Huanping GUO, Mingming LIU, Yang GAO, Lei ZHANG, Hang LI, Suzhu XIE, Ningning ZHANG
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2018-06-01
Series:Iranian Journal of Parasitology
Subjects:
Neospora caninum
Toxoplasma gondii
AMA1 gene
Recombinant adenovirus
Immune response
Online Access:https://ijpa.tums.ac.ir/index.php/ijpa/article/view/2206

Internet

https://ijpa.tums.ac.ir/index.php/ijpa/article/view/2206

Similar Items