microRNA in Extracellular Vesicles Released by Damaged Podocytes Promote Apoptosis of Renal Tubular Epithelial Cells

Tubular injury and fibrosis are associated with progressive kidney dysfunction in advanced glomerular disease. Glomerulotubular crosstalk is thought to contribute to tubular injury. microRNAs (miRNAs) in extracellular vesicles (EVs) can modulate distant cells. We hypothesized that miRNAs in EVs deri...

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Bibliographic Details
Main Authors: Jin Seok Jeon, Eunbit Kim, Yun-Ui Bae, Won Mi Yang, Haekyung Lee, Hyoungnae Kim, Hyunjin Noh, Dong Cheol Han, Seongho Ryu, Soon Hyo Kwon
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/6/1409