Impact of plasma xanthine oxidoreductase activity in patients with heart failure with preserved ejection fraction

Abstract Aims Reactive oxygen species are reportedly involved in the mechanism underlying heart failure with preserved ejection fraction (HFpEF); however, the disease pathophysiology remains poorly understood. Xanthine oxidoreductase (XOR), the rate‐limiting enzyme of purine metabolism, plays an imp...

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Bibliographic Details
Main Authors: Ken Watanabe, Tetsu Watanabe, Yoichiro Otaki, Tetsuro Shishido, Takayo Murase, Takashi Nakamura, Shigehiko Kato, Harutoshi Tamura, Satoshi Nishiyama, Hiroki Takahashi, Takanori Arimoto, Masafumi Watanabe
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:ESC Heart Failure
Subjects:
Online Access:https://doi.org/10.1002/ehf2.12734