An optimized negative-staining protocol of electron microscopy for apoE4•POPC lipoprotein

Apolipoprotein E (apoE), one of the major protein components of lipoproteins in the peripheral and central nervous systems, regulates cholesterol metabolism through its interaction with members of the low density lipoprotein receptor family. One key to understanding apoE function is determining the...

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Bibliographic Details
Main Authors: Lei Zhang, James Song, Yvonne Newhouse, Shengli Zhang, Karl H. Weisgraber, Gang Ren
Format: Article
Language:English
Published: Elsevier 2010-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752041079X