Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma.

Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma.

There are currently no established radiological parameters that predict response to immunotherapy. We hypothesised that multiparametric, longitudinal magnetic resonance imaging (MRI) of physiological parameters and pharmacokinetic models might detect early biological responses to immunotherapy for g...

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Bibliographic Details
Main Authors: Cecilie Brekke Rygh, Jian Wang, Marte Thuen, Andrea Gras Navarro, Else Marie Huuse, Frits Thorsen, Aurelie Poli, Jacques Zimmer, Olav Haraldseth, Stein Atle Lie, Per Øyvind Enger, Martha Chekenya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182474?pdf=render

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http://europepmc.org/articles/PMC4182474?pdf=render

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