Reconstruction of the cell entry pathway of an extinct virus.

Reconstruction of the cell entry pathway of an extinct virus.

Endogenous retroviruses (ERVs), remnants of ancient germline infections, comprise 8% of the human genome. The most recently integrated includes human ERV-K (HERV-K) where several envelope (env) sequences remain intact. Viral pseudotypes decorated with one of those Envs are infectious. Using a recomb...

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Bibliographic Details
Main Authors: Lindsey R Robinson-McCarthy, Kevin R McCarthy, Matthijs Raaben, Silvia Piccinotti, Joppe Nieuwenhuis, Sarah H Stubbs, Mark J G Bakkers, Sean P J Whelan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6095630?pdf=render

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http://europepmc.org/articles/PMC6095630?pdf=render

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