MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development.

Glioblastoma cells secrete extra-cellular vesicles (EVs) containing microRNAs (miRNAs). Analysis of these EV miRNAs in the bio-fluids of afflicted patients represents a potential platform for biomarker development. However, the analytic algorithm for quantitative assessment of EV miRNA remains under...

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Bibliographic Details
Main Authors: Johnny C Akers, Valya Ramakrishnan, Ryan Kim, Johan Skog, Ichiro Nakano, Sandeep Pingle, Juliya Kalinina, Wei Hua, Santosh Kesari, Ying Mao, Xandra O Breakefield, Fred H Hochberg, Erwin G Van Meir, Bob S Carter, Clark C Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3804457?pdf=render