Melatonin restores osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells and alleviates bone loss through the ///β-catenin axis

Background: Previous studies reported that melatonin exerts its effect on mesenchymal stem cell (MSC) survival and differentiation into osteogenic and adipogenic lineage. In the current study we aimed to explore the effect of melatonin on osteoporosis and relevant mechanisms. Methods: Real-time qual...

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Bibliographic Details
Main Authors: Jun Zhang, Guoliang Jia, Pan Xue, Zhengwei Li
Format: Article
Language:English
Published: SAGE Publishing 2021-08-01
Series:Therapeutic Advances in Chronic Disease
Online Access:https://doi.org/10.1177/2040622321995685