Reelin exerts structural, biochemical and transcriptional regulation over presynaptic and postsynaptic elements in the adult hippocampus

Reelin exerts structural, biochemical and transcriptional regulation over presynaptic and postsynaptic elements in the adult hippocampus

Reelin regulates neuronal positioning and synaptogenesis in the developing brain, and adult brain plasticity. Here we used transgenic mice overexpressing Reelin (Reelin-OE mice) to perform a comprehensive dissection of the effects of this protein on the structural and biochemical features of dendrit...

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Bibliographic Details
Main Authors: Carles eBosch, Ashraf JM Muhaisen, Lluis ePujadas, Eduardo eSoriano, Albert eMartinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Dendritic Spines
axon terminal
Electron microscopy
NMDA receptors
spine apparatus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00138/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00138/full

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