The efficacy of aspirin and metformin combination therapy in patients with rectal aberrant crypt foci: a double-blinded randomized controlled trial

The efficacy of aspirin and metformin combination therapy in patients with rectal aberrant crypt foci: a double-blinded randomized controlled trial

Abstract Background The incidence and mortality rates of colorectal cancer (CRC) continue to increase worldwide. Therefore, new preventive strategies are needed to lower the burden of this disease. Previous studies reported that aspirin could suppress the development of sporadic colorectal adenoma....

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Main Authors: Takuma Higurashi, Jun Arimoto, Keiichi Ashikari, Tomohiro Takatsu, Noboru Misawa, Tsutomu Yoshihara, Tetsuya Matsuura, Akiko Fuyuki, Hidenori Ohkubo, Atsushi Nakajima
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Cancer
Subjects:
Chemoprevention
Aspirin
Metformin
Combination therapy
Aberrant crypt foci
Online Access:http://link.springer.com/article/10.1186/s12885-020-07564-z

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http://link.springer.com/article/10.1186/s12885-020-07564-z

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