Effect of polymer type on characteristics of buccal tablets using factorial design

A two factor three level factorial design was used to investigate the effects of carbopol and cationic hydrophilic polymers which have a common use in buccal drug formulations. Statistical models with interaction terms were derived to evaluate influence of carbopol (X1) and chitosan (X2) on tablet d...

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Bibliographic Details
Main Authors: O. Esim, A. Savaser, C.K. Ozkan, Z. Bayrak, C. Tas, Y. Ozkan
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016417301883