Spermine inhibits Endoplasmic Reticulum Stress - induced Apoptosis: a New Strategy to Prevent Cardiomyocyte Apoptosis

Spermine inhibits Endoplasmic Reticulum Stress - induced Apoptosis: a New Strategy to Prevent Cardiomyocyte Apoptosis

Background/Aims: Endoplasmic reticulum stress (ERS) plays an important role in the progression of acute myocardial infarction (AMI), in part by mediating apoptosis. Polyamines, including putrescine, spermidine, and spermine, are polycations with anti-oxidative, anti-aging, and cell growth-promoting...

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Bibliographic Details
Main Authors: Can Wei, Yuehong Wang, Meixiu Li, Hongzhu Li, Xiaoxiao Lu, Hongjiang Shao, Changqing Xu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Acute myocardial infarction
Spermine
ERS
ROS
Apoptosis
PERK-eIF2α pathway
Online Access:http://www.karger.com/Article/FullText/438648

Internet

http://www.karger.com/Article/FullText/438648

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