Importance of Endocytosis for the Biological Activity of Cedar Virus Fusion Protein

Endocytosis plays a particular role in the proteolytic activation of highly pathogenic henipaviruses Hendra (HeV) and Nipah virus (NiV) fusion (F) protein precursors. These proteins require endocytic uptake from the cell surface to be cleaved by cellular proteases within the endosomal compartment, f...

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Bibliographic Details
Main Authors: Kerstin Fischer, Martin H. Groschup, Sandra Diederich
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/9/2054