Alterations in Cortical Thickness in Young Male Patients With Childhood-Onset Adult Growth Hormone Deficiency: A Morphometric MRI Study

Alterations in Cortical Thickness in Young Male Patients With Childhood-Onset Adult Growth Hormone Deficiency: A Morphometric MRI Study

BackgroundThe growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis plays an important role in brain structure and maintenance of brain function. There is a close correlation between serum GH and IGF1 levels and age-related cognitive function. The effects of childhood-onset growth hormone de...

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Bibliographic Details
Main Authors: Hongbo Yang, Kang Li, Xinyu Liang, Bin Gu, Linjie Wang, Gaolang Gong, Feng Feng, Hui You, Bo Hou, Fengying Gong, Huijuan Zhu, Hui Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Neuroscience
Subjects:
childhood-onset adult growth hormone deficiency
cortical thickness
structure MRI
growth hormone
insulin-like growth factor 1
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01134/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.01134/full

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