Blocking the CD47-SIRPα axis by delivery of anti-CD47 antibody induces antitumor effects in glioma and glioma stem cells

Blocking the CD47-SIRPα axis by delivery of anti-CD47 antibody induces antitumor effects in glioma and glioma stem cells

Tumor initiating cells or cancer stem cells (CSCs) play an important role in the initiation, development, metastasis, and recurrence of tumors. However, traditional therapies have limited effects against CSCs and targeting these cells is crucial when developing new therapeutic strategies against can...

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Bibliographic Details
Main Authors: Feng Li, Bingke Lv, Yang Liu, Tian Hua, Jianbang Han, Chengmei Sun, Limin Xu, Zhongfei Zhang, Zhiming Feng, Yingqian Cai, Yuxi Zou, Yiquan Ke, Xiaodan Jiang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-02-01
Series:OncoImmunology
Subjects:
cd47
immunotherapy
human glioblastoma
cancer stem cells
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1391973

Internet

http://dx.doi.org/10.1080/2162402X.2017.1391973

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