Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1

Holliday junctions (HJs) are DNA intermediates in genetic recombination that are resolved by nuclease, termed resolvase, to ensure genome stability. Here, the authors provide insights into the resolution process by resolving the crystal structure of the chloroplast resolvase MOC1 with HJs substrates...

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Bibliographic Details
Main Authors: Junjie Yan, Sixing Hong, Zeyuan Guan, Wenjing He, Delin Zhang, Ping Yin
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15242-8