Pathway and mechanism of pH dependent human hemoglobin tetramer-dimer-monomer dissociations.

Hemoglobin dissociation is of great interest in protein process and clinical medicine as well as in artificial blood research. However, the pathway and mechanisms of pH-dependent human Hb dissociation are not clear, whether Hb would really dissociate into monomers is still a question. Therefore, we...

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Bibliographic Details
Main Authors: Yao-Xiong Huang, Zheng-Jie Wu, Bao-Tian Huang, Man Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3842943?pdf=render