Early changes in neural circuit function engaged by negative emotion and modified by behavioural intervention are associated with depression and problem-solving outcomes: A report from the ENGAGE randomized controlled trial

Background: Depression exerts a staggering toll that is worsened with co-occurring chronic conditions such as obesity. It is imperative to develop more effective interventions for depression and to identify objective and biological plausible neural mechanisms to understand intervention outcomes. The...

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Bibliographic Details
Main Authors: Andrea N Goldstein-Piekarski, Joseph Wielgosz, Lan Xiao, Patrick Stetz, Carlos G. Correa, Sarah E. Chang, Nan Lv, Lisa G. Rosas, Philip W. Lavori, Mark B. Snowden, Elizabeth M. Venditti, Janine M. Simmons, Joshua M. Smyth, Trisha Suppes, Megan A. Lewis, Olusola Ajilore, Jun Ma, Leanne M. Williams
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421001808