An elastic element in the protocadherin-15 tip link of the inner ear

Tip-link filaments convey force to activate hair cells, important sensory receptors. Here the authors solve a partial structure of human protocadherin-15, a tip-link component with an unusual Ca2+–free linker that bends and is predicted to confer flexibility to this filament during inner-ear mechano...

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Bibliographic Details
Main Authors: Raul Araya-Secchi, Brandon L. Neel, Marcos Sotomayor
Format: Article
Language:English
Published: Nature Publishing Group 2016-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13458