Interferon targeted therapies in systemic lupus erythematosus
Type I interferons secreted by plasmacytoid dendritic cells (pDCs) play a crucial role in the pathogenesis of systemic lupus erythematosus by driving the formation of autoantibodies against nuclear debris. Inherited mutations causing activation of the Type I interferon pathway result in a phenotype...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
PCO Convin S.A.
2017-01-01
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| Series: | Mediterranean Journal of Rheumatology |
| Subjects: | |
| Online Access: | https://www.mjrheum.org/assets/files/792/file73_945.pdf |