Combined Treatment With CCR1-Overexpressing Mesenchymal Stem Cells and CCL7 Enhances Engraftment and Promotes the Recovery of Simulated Birth Injury-Induced Stress Urinary Incontinence in Rats

Combined Treatment With CCR1-Overexpressing Mesenchymal Stem Cells and CCL7 Enhances Engraftment and Promotes the Recovery of Simulated Birth Injury-Induced Stress Urinary Incontinence in Rats

Objective: To observe whether urethral injection of chemokine (c-c motif) ligand 7 (CCL7) and overexpressing CC receptor 1 (CCR1) in mesenchymal stem cells (MSCs) can promote their homing and engraftment to the injured tissue, and improve the recovery of simulated birth injury-induced stress urinary...

Full description

Bibliographic Details
Main Authors: Hai-Hong Jiang, Ling-Xiao Ji, Hai-Yan Li, Qi-Xiang Song, Yasmeen Bano, Lei Chen, Guiming Liu, Meihao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Surgery
Subjects:
stress urinary incontinence
mesenchymal stem cell
chemokine (c-c motif) ligand 7
chemokine (c-c motif) receptor 1
rat model
birth injury
Online Access:https://www.frontiersin.org/article/10.3389/fsurg.2020.00040/full

Internet

https://www.frontiersin.org/article/10.3389/fsurg.2020.00040/full

Similar Items