T-cell Redirecting Therapies for the Treatment of B-cell Lymphomas: Recent Advances

T-cell specificity can be redirected against tumor antigens either ex vivo using engineered chimeric antigen receptor (CAR) T-cells or in vivo by bridging natural T-cells and tumor cells with bispecific T-cell engager (TCE) antibodies. Currently, four CAR T-cells have been approved by the FDA for th...

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Bibliographic Details
Main Authors: Ondine Messéant, Roch Houot, Guillaume Manson
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/17/4274