Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mices⃞

Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mices⃞

To elucidate the separate contributions of the lipolytic versus ligand-binding functions of hepatic lipase (HL) to lipoprotein metabolism and atherosclerosis, and to investigate the role of the low density lipoprotein receptor (LDLr) in these processes, we compared mice expressing catalytically acti...

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Bibliographic Details
Main Authors: Lita Freeman, Marcelo J.A. Amar, Robert Shamburek, Beverly Paigen, H. Bryan Brewer, Jr., Silvia Santamarina-Fojo, Herminia González-Navarro
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Lipid Research
Subjects:
low density lipoprotein receptor
lipase
lipoprotein metabolism
aortic atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520436417

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http://www.sciencedirect.com/science/article/pii/S0022227520436417

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