Oxidative stress and lipid peroxidation are upstream of amyloid pathology

Oxidative stress is a common feature of the aging process and of many neurodegenerative disorders, including Alzheimer's disease. Understanding the direct causative relationship between oxidative stress and amyloid pathology, and determining the underlying molecular mechanisms is crucial for th...

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Bibliographic Details
Main Authors: Muriel Arimon, Shuko Takeda, Kathryn L. Post, Sarah Svirsky, Bradley T. Hyman, Oksana Berezovska
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115002314