Heparanase isoform expression and extracellular matrix remodeling in intervertebral disc degenerative disease

Heparanase isoform expression and extracellular matrix remodeling in intervertebral disc degenerative disease

OBJECTIVE: To determine the molecules involved in extracellular matrix remodeling and to identify and quantify heparanase isoforms present in herniated and degenerative discs. INTRODUCTION: Heparanase is an endo-beta-glucuronidase that specifically acts upon the heparan sulfate chains of proteoglyca...

Full description

Bibliographic Details
Main Authors: Luciano Miller Reis Rodrigues, Thérèse Rachell Theodoro, Leandro Luongo Matos, Ana Maria Mader, Carlo Milani, Maria Aparecida da Silva Pinhal
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2011-01-01
Series:Clinics
Subjects:
Intervertebral degeneration
Herniated disc
Heparanase
Extracellular matrix
Proteoglycan
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000500030

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000500030

Similar Items