Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome.

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome.

The opportunistic intracellular pathogen Legionella pneumophila is the causative agent of Legionnaires' disease. L. pneumophila delivers nearly 300 effector proteins into host cells for the establishment of a replication-permissive compartment known as the Legionella-containing vacuole (LCV). S...

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Bibliographic Details
Main Authors: Xi Luo, David J Wasilko, Yao Liu, Jiayi Sun, Xiaochun Wu, Zhao-Qing Luo, Yuxin Mao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004965

Internet

https://doi.org/10.1371/journal.ppat.1004965

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