Inhibitory Effects of Benzaldehyde Derivatives from the Marine Fungus Eurotium sp. SF-5989 on Inflammatory Mediators via the Induction of Heme Oxygenase-1 in Lipopolysaccharide-Stimulated RAW264.7 Macrophages

Inhibitory Effects of Benzaldehyde Derivatives from the Marine Fungus Eurotium sp. SF-5989 on Inflammatory Mediators via the Induction of Heme Oxygenase-1 in Lipopolysaccharide-Stimulated RAW264.7 Macrophages

Two benzaldehyde derivatives, flavoglaucin (1) and isotetrahydro-auroglaucin (2), were isolated from the marine fungus Eurotium sp. SF-5989 through bioassay- and 1H NMR-guided investigation. In this study, we evaluated the anti-inflammatory effects of these compounds in lipopolysaccharide (LPS)-sti...

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Bibliographic Details
Main Authors: Kyoung-Su Kim, Xiang Cui, Dong-Sung Lee, Wonmin Ko, Jae Hak Sohn, Joung Han Yim, Ren-Bo An, Youn-Chul Kim, Hyuncheol Oh
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
benzaldehyde derivatives
marine fungus
Eurotium rubrum
RAW264.7 macrophages
heme oxygenase-1
anti-inflammatory effect
nuclear factor-κB
Online Access:http://www.mdpi.com/1422-0067/15/12/23749

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http://www.mdpi.com/1422-0067/15/12/23749

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