Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection.

Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection.

Although combination antiretroviral therapy (cART) initiated in the acute phase of HIV-1 infection may prevent expansion of the latent reservoir, its benefits remain controversial. In the current study, HIV-1 RNA transcription patterns in peripheral blood mononuclear cells (PBMC) were monitored duri...

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Bibliographic Details
Main Authors: Adrian Schmid, Sara Gianella, Viktor von Wyl, Karin J Metzner, Alexandra U Scherrer, Barbara Niederöst, Claudia F Althaus, Philip Rieder, Christina Grube, Beda Joos, Rainer Weber, Marek Fischer, Huldrych F Günthard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2953504?pdf=render

Internet

http://europepmc.org/articles/PMC2953504?pdf=render

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